Conceptual 3D model of adeno-associated virus in shades of purple.

eBook

Understanding AAV Gene Therapy Development

Discover a data-driven guide to successful gene therapy.

Brought to you byLonza

Successful adeno-associated virus (AAV) production is the cornerstone of gene therapy development. However, navigating the road from target identification and validation to high titers and full capsids can be challenging. Moreover, researchers often struggle with maximizing purification, quality attributes, and analytics for downstream processing success.

Download this ebook to learn about the basics and best practices of AAV gene therapy development from AAV development to getting to investigational new drug status.

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The Scientist October Digest cover

October 2026

Antarctica’s Blood Falls Teems With Mysterious Microbial Life

Miles away from the closest ocean, marine microbes thrive in the red ice and mud around Blood Falls, offering clues to microbial adaptation and past climate events.

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Evaluating Blood Biomarkers for Alzheimer’s Disease Staging

Evaluating Blood Biomarkers for Alzheimer’s Disease Staging

Explore how blood-based biomarkers perform across Alzheimer’s disease stages, including AIBL Study findings comparing p-Tau217 and other markers against amyloid-beta and tau PET reference standards.

Find better biologics faster with Stunner and the AI Developability Workcell

Find better biologics faster with Stunner and the AI Developability Workcell

Learn how microvolume UV/Vis and DLS can accelerate, automate, and streamline protein developability screening while reducing sample requirements.

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Choose clarity. Choose speed. Choose MyMass™

Assess protein sample purity and homogeneity in minutes with mass photometry using only nanograms of sample.

Characterizing LNP Heterogeneity With Super-Resolution Imaging

Characterizing LNP Heterogeneity With Super-Resolution Imaging

Explore how super-resolution microscopy enables particle-level characterization of lipid nanoparticle composition, cargo loading, heterogeneity, and stability, providing complementary insights for formulation development and optimization.

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Stellaromics Expands Pyxa Adoption as Instruments are Installed at Leading Research Institutions Across the U.S. and EuropeStellaromics, Inc., the leader in 3D

The placements follow the commercial launch of Pyxa at the Advances in Genome Biology and Technology (AGBT) meeting in February 2026 and mark the company's transition from Early Access into global commercial availability.

3D rendered chromatin with DNA helix in the background

CUTANA™ ATAC-seq Kit: Robust Results from Low Inputs

Generate robust, reproducible ATAC-seq data from as few as 1,000 nuclei. The CUTANA™ ATAC-seq Kit uses validated reagents, pre-charged Tn5 and a streamlined workflow, yielding high-quality data with less troubleshooting at a low cost per reaction.

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CellRaft AIR: Find the Right Antibody-Producing Cells Faster

The CellRaft AIR streamlines antibody discovery with imaging, functional screening, and gentle isolation of viable single B cells and hybridomas, helping verify monoclonality and identify high producing clones faster.

Maxwell® Rapid ccfDNA Kit

Maxwell® Rapid ccfDNA Kit: Automated Purification of ccfDNA in Under 30 Minutes

Load plasma directly into prefilled cartridges, no pretreatment, no ethanol. Under 30 minutes of instrument run time, up to 48 samples in parallel, with a high-throughput format also available.