Short-read RNA-seq provides robust gene-level expression but is limited in resolving full-length transcripts and splice variants. Long-read sequencing addresses these limitations by capturing complete isoforms, enabling direct interrogation of transcript structure and isoform-specific changes. This information can identify biomarkers and support therapeutic development.
Download this case study to learn more about how full-length transcript sequencing can detect treatment-associated splice variants and characterize transcriptome-wide expression changes.
