Notable

The Faculty of 1000 is aWeb-based literature awareness tool published by BioMed Central. For more information visit www.facultyof1000.com. TASTE TRANSDUCTION J.I. Glendinning et al., "A high-throughput screening procedure for identifying mice with aberrant taste and oromotor function," Chemical Senses, 27[5]:461-74, June 2002. "Screening for taste transduction is particularly problematic because of the low throughput--lengthy duration and indirect nature--of the traditional 'two-bottle prefer

Jeffrey Perkel
Jul 7, 2002
The Faculty of 1000 is a
Web-based literature awareness tool published by BioMed Central. For more information visit www.facultyof1000.com.

TASTE TRANSDUCTION
J.I. Glendinning et al., "A high-throughput screening procedure for identifying mice with aberrant taste and oromotor function," Chemical Senses, 27[5]:461-74, June 2002.

"Screening for taste transduction is particularly problematic because of the low throughput--lengthy duration and indirect nature--of the traditional 'two-bottle preference' assay. Glendinning et al. describe a faster and more accurate methodology to assay taste in mice and pave the way for analyzing the large number of transgenic mouse strains that are being generated in labs world-wide."

--Stephen Roper,
University of Miami School of Medicine, US

NEW HUNTINGTON MODEL
L.P. de Almeida et al., "Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length," Journal of Neuroscience...