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Understanding the Molecular Mechanisms of Synthetic Cannabinoid Receptor Agonists

Biosensing plays a fundamental role in the latest technology that sheds light on how G protein-coupled receptors are activated by synthetic cannabinoid receptor agonists.

Written byBMG LABTECH and The Scientist Staff
| 1 min read
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G protein-coupled receptors (GPCRs) are important in health and disease. They allow cellular entry of hormones, neurotransmitters, therapeutics, and drugs such as cannabinoids. A novel cAMP bioluminescence biosensor system, known as CAYMEL BRET, helps researchers understand how synthetic cannabinoid receptor agonists (CRAs) activate GPCRs.1

BMG Labtech’s PHERAstar® FS microplate reader helps researchers evaluate the function and toxicity profiles of synthetic cannabinoid receptor agonists.

designed by erin lemieux

Learn more about how cAMP bioluminescence biosensing informs synthetic cannabinoid research.

  1. Sachdev S, et al. Pharmacol Res Perspect. 2020.
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