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Ticker Tape Technology Records Cell History
Researchers developed a novel protein fiber that tracks transcriptional events over time in living cells. This could shine a light on gene regulation during development or after cellular perturbations.
Danielle is an Assistant Editor at The Scientist. She has a background in neuroscience and molecular psychiatry. She has previously written for BioTechniques News, The Scientist, and Drug Discovery News.
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New tools for tracking changes in gene expression with spatiotemporal precision could illuminate mechanisms driving development or disease progression. Inspired by the history recorded in tree rings, researchers developed a novel technology that records transcriptional events as fluorescent tags onto elongating protein chains embedded inside cells.1
DESIGNED BY ERIN LEMIEUX
- Lin D, et al. Nat Biotechnol. 2023;41:631-639.
- Baskaran Y, et al. Nat Commun. 2015;6:8681.
