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Despite its popularity, the science and regulations sur- rounding microbiome testing are still catching up, high- lighting the need for better standards and oversight.

Regulatory Gaps Plague At-Home Microbiome Tests

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies. 

Fluorescent microscopy of a fly embryo stained with five antibodies. Along the bottom, from left to right, the following colors appear representing unique homeobox (Hox) proteins: Magenta, Green, Yellow, and Red. Vertical cyan stripes appear above this line of colors, and in the middle of the embryo behind these strips is orange staining. 

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The Scientist Digest cover September 2026

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Multiplex Microscopy Becomes Easier with Encoded Antibodies

TS Digest

Epigenetics in Evolution

Modified cover of Epigenetics in Evolution.

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Cartoon of a sea lion clapping at people.

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Ten Minute Sabbatical

Crossword Puzzle

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Opinion: The Problem with Researchers Hoarding Resources

Opinion

A new study suggests that W. virgo hasn&rsquo;t suffered the sort of genetic deterioration that often plagues asexually reproducing species.

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When the sexually reproducing grasshopper species Warramaba whitei (left) and Warramaba flavolineata (right) mated around 250,000 years ago, they made Warramaba virgo (center), which has been cloning itself ever since.

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How a Grasshopper Gave Up Sex, Took Up Cloning

Feature

A breeding program that started with two males and two females of Ecuador&rsquo;s longnose harlequin toad (Atelopus longirostris), once thought extinct, now has dozens of adults and hundreds of juveniles and tadpoles.

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Cartoon of a scientist trying to discover an extinct species.

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Botanists celebrate their discovery of what may be the world&rsquo;s last lateleaf oak tree (Quercus tardifolia).

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Fernanda, a Fernandina giant tortoise (Chelonoidis phantasticus), was identified in 2019, decades after her species supposedly went extinct.

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Fuzz on the underside of this leaf helped botanists identify the tree as a lateleaf oak (Quercus tardifolia).

When an Extinct Species Is Found Alive, What Happens Next?

Epigenetics and the genome infographic, the shaping mutation patterns graphic

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Epigenetics and the genome infographic, the new gene functions graphic

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Epigenetics and the genome infographic, the dampening mutation patterns graphic

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Epigenetics and the genome infographic, the triggering mutations graphic

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Do Epigenetic Changes Influence Evolution? 

Illustration from the epigenetics and the genome infographic

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Infographic: How Epigenetic Marks Can Change the Genome

Infographic

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Steve Ramirez Reshapes Memories in the Brains of Mice

Profile

In the 1920s, the Institute for Sexual Research in Berlin was a haven for queer people, many of whom came to the institute seeking to express their identities without fear of being imprisoned. This undated photo depicts a costume party at the institute; its founder, Magnus Hirschfeld (second from right, in glasses), can be seen holding hands with his partner, Karl Giese (center).

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A black and white photo of roughly a dozen people in costume

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Trans Medicine, 1919

Foundations

Researchers debate the influence of extragenomic processes on evolutionary change