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Immunofluorescence light microscopy image of cancer cells growing in 2D with nuclei in blue, cytoplasm in red, and DNA damage foci in green.
Shining a Light on New Microscopy Technologies
From the advent of optical microscopes to today, light microscopy methods have been central to life science discoveries across disciplines.
Shining a Light on New Microscopy Technologies
Shining a Light on New Microscopy Technologies

From the advent of optical microscopes to today, light microscopy methods have been central to life science discoveries across disciplines.

From the advent of optical microscopes to today, light microscopy methods have been central to life science discoveries across disciplines.

Research Product Blogs

A researcher removes a tube rack from an ultra-low temperature freezer with frost build-up.
Holistic Freezer Sustainability Goes Beyond Energy Certification
The Scientist and Stirling Ultracold | Oct 2, 2024 | 3 min read
Product efficiency requirements help combat the environmental cost of ultra-low temperature freezers, but there is more to sustainability than standardized energy ratings.
An illustration of an adeno-associated virus.
Streamlining Viral Gene Therapy Development
The Scientist and Charles River Laboratories, Inc. | Aug 27, 2024 | 3 min read
Off-the-shelf and custom plasmid DNA and viral vector products help scientists take their gene therapy research to the next level.
A person typing at a laptop computer, with a digital overlay showing multiple files coming together to a central point.
A Unifying Data Informatics Approach for Multimodal Research
The Scientist and Sapio Sciences | Jun 4, 2024 | 4 min read
As drug research becomes more interdisciplinary, data informatics needs to keep up and accommodate a diverse array of inputs and requirements. 
An illustration of cells growing in the presence of cytokines.
Advancing Immunotherapy Development with High-Quality Cytokines
The Scientist and Sino Biological | May 22, 2024 | 3 min read
Superior quality cytokines are crucial for reliable research results and the safe production of cancer cell therapies.
Researchers can obtain epigenetic information in addition to genetic insights from a single DNA sample.
The Six-Base Genome Reveals Multimodal Data from a Single DNA Sample
The Scientist and biomodal | Mar 12, 2024 | 4 min read
To gather multiomic insights, researchers used to combine data from multiple workflows, but duet evoC provides more information from less sample in one workflow.
<span dir="ltr" >Abstract</span><span dir="ltr">&nbsp;</span><span dir="ltr">illustration of ultraviolet light beams</span><span dir="ltr">.</span>
Obtaining High-Quality Acrylamide Gels without Compromises
The Scientist Creative Services Team in collaboration with MilliporeSigma | Feb 26, 2024 | 3 min read
Discover how a novel acrylamide gel casting system allows researchers to quickly acquire high-quality results.
Conceptual vector illustration depicting CRISPR gene editing by scientists for medical applications.
Optimizing Gene Editing with PARP1 CRISPR Plasmids 
The Scientist and Santa Cruz Biotechnology, Inc. | Jan 24, 2024 | 3 min read
CRISPR plasmids provide a robust solution for streamlining human cell transfection workflows.   
Abstract conceptual image of white and blue culture cells on blue background.
A Sticky Situation: Optimizing Cell Culture with Essential Extracellular Matrix Proteins
The Scientist and MilliporeSigma | Nov 20, 2023 | 3 min read
Pre-mixed attachment factors provide a robust solution to streamlining cell culture workflows.
A microscopy image of intestinal crypts in human tissue.
Trust Your Gut: Screening Drugs Using Novel Intestinal Models
The Scientist and Altis Biosystems | Nov 14, 2023 | 4 min read
Discover how cutting-edge nonclinical in vitro models better recapitulate the human gastrointestinal tract.
PCR tubes placed into the 96-well loading chamber of a PCR thermocycler instrument.
Directing Superior Reagents for Better PCR Results
The Scientist and MilliporeSigma | Oct 2, 2023 | 3 min read
Directed evolution approaches are creating new reagents to help a tried-and-true technique reach new heights.
3D rendered illustration of the human gastrointestinal tract with an inset close up of the epithelium.
Exploring Preclinical Models for Inflammatory Bowel Disease
The Scientist and Altis Biosystems | Sep 15, 2023 | 4 min read
Learn how epithelial monolayer models help researchers discover effective therapies and biomarkers for inflammatory bowel diseases.
A photo of a scientist working with an EpMotion&reg; liquid handler.
Simplifying Liquid Handling Workflows with Automation
The Scientist and Eppendorf | Aug 21, 2023 | 3 min read
Learn about the legacy of liquid handling in molecular breakthroughs and how effortless automation enables more accurate and precise research processes.
Sino Biological&nbsp;
Introducing GMP-Grade Recombinant Cytokines for Stem Cell Research
The Scientist and Sino Biological | Aug 21, 2023 | 3 min read
Cutting edge technology delivers cytokines with high purity, high bioactivity, high batch-to-batch consistency, and high stability.
A microscopy image of an apical-out colon organoid that was produced using MilliporeSigma&rsquo;s protocol.
Turning Organoids Inside Out 
The Scientist, MilliporeSigma, and Hub Organoids | Aug 15, 2023 | 4 min read
Discover how a new procedure reverses the polarity of typical basolateral-out organoids to form versatile apical-out organoids.
A 3D rendering of an albumin&rsquo;s protein structure.
Providing Stability In Vivo, In Vitro, and In Culture
The Scientist and MilliporeSigma | Aug 15, 2023 | 3 min read
Albumins enable researchers to bind, sequester, and stabilize important molecules across research applications.
A 96-well plate with wells spelling out &ldquo;ANIMAL COMPONENT FREE&rdquo;. &nbsp;
Animal Component-Free Reagents Unleash Cell Culture’s True Potential 
The Scientist and MilliporeSigma | Aug 9, 2023 | 3 min read
The latest synthetic and chemical reagents offer researchers more flexibility, stability, and consistency when working with their cells.
A multicolored illustration of a cell undergoing division.
See Beyond the Scatter Plot with Imaging, Spectral Flow Cytometry
The Scientist and BD Biosciences | Aug 9, 2023 | 3 min read
A novel instrument combines fluorescence-activated cell sorting, imaging flow cytometry, and spectral flow cytometry to advance cell population examination.
A blood sample containing white and red blood cells.
Enhancing Cell Morphology-Based Analysis
The Scientist and Deepcell | Aug 3, 2023 | 3 min read
Learn how the latest AI-driven technology uses morphology to comprehensively analyze and sort cell populations.
Lipofuscin autofluorescence was quenched using EverBrite TrueBlack&reg; Hardset Mounting Medium&reg;, allowing effective visualization of glial cells (GFAP antibody stain, cyan) and cell nuclei (magenta) in human cerebral cortex cryosections.
Stepping Out of the Background
The Scientist and Biotium | Jul 27, 2023 | 4 min read
New developments in non-specific fluorescence quenching offer researchers clearer pictures and more multiplexing possibilities.
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