Image of forensic scientist Mitchell Holland. In the background there is someone in a white jumpsuit standing in front of caution tape.

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Image of a forensic scientist holding a magnifying glass to DNA to reveal a DNA fingerprint.

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Image of a forensic scientist holding a magnifying glass to DNA to reveal a DNA fingerprint. 

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DNA Profiling: Tracing Killers and Solving Mysteries Using Genetic Clues

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Photo of Holowatyj wearing a white lab coat. She is sitting at a laboratory bench and pipetting a liquid from a falcon tube.

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Illustration of a young adult looking at their phone as they walk through an arrow that is pointing up. An illustration of a colon is in the background.

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Generation X and Millennials Face a Steep Rise in Early-Onset Colorectal Cancer Cases

A red male cardinal and a brownish female sit on a branch in front of a green background.

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A black and white image of Nettie Stevens wearing a high-necked dress and a large hat.

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Richel Meisel wears a red collared shirt and stands in front of a light background.

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A tank filled with small fish in the laboratory.

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Judith Mank and a handful of other researchers observe tanks of guppies in the laboratory.

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A small brown mouse with a white underbelly.

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An underwater image of a snorkeler over a coral reef.

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Sex Determination: It&rsquo;s in the Genes&mdash;Sometimes

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Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against cancer.

Peto's Paradox: How Gigantic Species  Evolved to Beat Cancer

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

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Study Confirms Safety of Genetically Modified T Cells

TS Digest

Gut-Powered Mosquito Probes

Two male scientists working in a laboratory.

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Image of Mari&agrave; Alemany Lamana, an emeritus professor of Biochemistry and Nutrition, who led a research group at the Balearic Islands University studying early chick development. He is facing the camera, dressed in a suit and wearing glasses.

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A Matter of Molecular Attraction

Article

A photo of the Twist Bioscience cfDNA library preparation kit

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Conceptual image of hands wearing surgical gloves holding a test tube filled with a liquid biopsy sample.

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Twist Bio

Twist Bioscience

Enhanced Sequencing Results from Liquid Biopsies

The first panel in a schematic of a modified probe, JFT1, used with a peroxidase (APEX2). APEX2, a yellow square, is shown to be on lysosomes, while Mitochondria are shown green with mEosEm, a fluorescent protein. The second panel is an insert of the lysosomal membrane with APEX2 bound to a blue lysosomal transmembrane protein. A grey, a green, and a purple membrane protein are also present. In the third panel, JFT1 has reacted with hydrogen peroxide and APEX2 to create red fluorescence near APEX2 that remains separate from the green mitochondria. The final panel is an insert showing the lysosomal membrane with activated JFT1, depicted as red spiky shapes, bound to the three other nearby membrane proteins or itself.

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JFT1 has reacted with hydrogen peroxide and APEX2 to create red fluorescence near APEX2 that remains separate from the green mitochondria.

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FLEXing a Bright New Idea

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A photo of a microplate loaded onto the FLUOstar&reg; Omega&rsquo;s plate carrier.

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An illustration of neurons surrounded by protein aggregates.

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BMG LABTECH

Accelerating Protein Aggregation Analysis

Image of John Jewett, a biochemist at the University of Arizona, who works on reactive probes designed to be released in biological environments. He is smiling at the camera and is wearing a pair of black glasses and a black shirt.

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Researchers at the University of Arizona developed a pH-responsive probe that activated in the basic environment (purple) of the larval midgut and bound to gut proteins.

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Image of Michael Riehle, a vector biologist at the University of Arizona, who conducts mosquito research focusing on mosquito physiology. He is smiling at the camera against a green background and is wearing a blue collared shirt.

A computer monitor shows a video of two people sitting side by side singing and playing a guitar together.

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Image of Barbara Di Ventura, a synthetic biologist at the University of Freiburg, who turns her research findings into short musical synopses. She is facing the camera and is wearing a white and black striped shirt.

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The Soundtrack of Science

Interview

A photo of Tomohisa Toda, a neuroscientist at the University of Erlangen-Nuremberg. He is in his laboratory, seated in front of a microscope.

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A brain section showing the mouse hippocampus. RNA molecules are shown in red.

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Long Live the RNA

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Science Crossword Puzzle

Crossword Puzzle

With the rise of insecticide resistance, researchers crafted a novel probe that selectively targets mosquito larvae’s weak spot.