An abstract illustration of a tooth on a bluish background, signifying teeth that are a source of multipotent dental stem cells that can have therapeutic applications in dental diseases and beyond.

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Stem cells in the teeth and gums are multipotent and easily accessible. Scientists are researching ways to harness their power for therapies beyond dentistry.

Dental Stem Cells Regenerate More Than Just Smiles

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

A Stubborn Gene, a Failed Experiment, and a New Path

TS Digest

An illustration of James Trosko, now a cancer biologist at Michigan State University, with long brown hair and close beard wearing a white lab coat on the right of the image. He is holding a cell culture plate and looking at it inquiringly. On the left is a call out showing where, in the cell culture dish, pink, irregular cells are sitting close to one another. The background is an image of these same cells in a green overlay.

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A Mystery Result Caused a Hypothesis Reckoning

Article

Image of Lego DNA which features a sugar-phosphate backbone with base-pair molecular structures.

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Image of five LEGO Minifigures representing: Rosalind Franklin, Maurice Wilkins, Franklin's PhD student Raymond Gosling, Francis Crick, and James Watson. On the blackboard behind these figures are notes from Franklin’s notebook on the parameters of DNA.

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Lego DNA: Building the Double Helix, Brick by Brick

Science Snapshot

Image of a man in a laboratory looking frustrated with his failed experiment.

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Chimeric antigen receptors expressed by a T cell binding to the membrane surface receptor on a cancer cell

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ACRO Biosystems

Making In Vivo Progress in CAR Therapeutic Development

Blue, green, and red dots make a worm-like shape against a black background, signifying human organoids grafted in mice that secreted insulin. 

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Reprogrammed Human Stomach Organoids Secrete Insulin

The Nutshell

A photograph of François Haman, who studies energy metabolism and nutrition in extreme environments including cold.

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François Haman, who studies energy metabolism and nutrition in extreme environments including cold, sits in a cold-water immersion tank in a snowy landscape.

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A woman walks under snowfall on a city street. Signifies that some people feel cold temperatures more than others.

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

A Mystery Result Caused a Hypothesis Reckoning

Lego DNA: Building the Double Helix, Brick by Brick

A Stubborn Gene, a Failed Experiment, and a New Path

Making In Vivo Progress in CAR Therapeutic Development

Reprogrammed Human Stomach Organoids Secrete Insulin

Why Do Some People Feel Cold When Others Don’t?