An abstract illustration of a tooth on a bluish background, signifying teeth that are a source of multipotent dental stem cells that can have therapeutic applications in dental diseases and beyond.

12-25-q4-cover

Stem cells in the teeth and gums are multipotent and easily accessible. Scientists are researching ways to harness their power for therapies beyond dentistry.

Dental Stem Cells Regenerate More Than Just Smiles

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus. 

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.

01-26-digest-article-images-amniotic-fluid-1800-x-720

87527-jan-digest-ac-cover-8-5-x-10-5

What Is the Amniotic Fluid Composed of? 

TS Digest

A Nanoparticle Delivery System for Gene Therapy

Image of a DNA strand with a magnifying glass hovering over one section (left). A sweating man lifts his arm and emits body odor with a callout depicting that he has yellow colored earwax (right).

75365-ts-feb-02-25-digest-ac-earwax-bodyodor-article

Image of Julie Horvath. She smiles at the camera and wears a green shirt.

headshot-chris

Image of Chris Callewaert. He smiles at the camera and wears a blue and white striped shirt.

75365-ts-feb-02-25-digest-ac-earwax-bodyodor-banner

How Are Earwax and Body Odor Linked?

Explainer

An illustration of RNA molecules on a colorful background.

74226-02-25-techhighlight-scalebio-1800x1260

74226-02-25-techhighlight-scalebio-banner

An overview of the scRNA-seq workflow with ScalePlex multiplexing technology.

scaleplex-workflowv2-digest

ScaleBiosciences-logo

Scale Biosciences

Elevate Single-Cell RNA Sequencing with Advanced Multiplexing

Article

A CRISPR-Cas platform uses microfluidic droplets, encasing CRISPR components and DNA barcodes, and injects individual droplets into zebrafish embryos. The embryos are raised and then researchers link phenotypes to genotypes by sequencing the barcodes.

02-25-mic-drop-infographic

75365-ts-feb-02-25-digest-ac-article-images-1800-x-1260

DNA Droplets in Motion Accelerate Gene Discovery

Infographic

Krista Beardy stands next to a microscope wearing a white lab coat.

lab-photo

Scientist using a Sharpie to label Petri plates.

75365-ts-feb-02-25-digest-ac-labels-1800-x-1260

75365-ts-feb-02-25-digest-ac-labels-banner

The Mystery of the Disappearing Labels

3D illustration of a gold lipid nanoparticle with pink nucleic acid inside of it. Purple and teal spikes stick out from the lipid bilayer representing polyethylene glycol.

75365-ts-feb-02-25-digest-ac-nanoparticle-1800-x-1260

75365-ts-feb-02-25-digest-ac-nanoparticle-banner

Photograph of a group of people aligned in two rows with wildflowers and shrubs in the background. John Lewis, a cancer biologist and the founder and CEO of Entos Pharmaceuticals, stands seventh in the front row seventh in from the right wearing a light shirt and blue jeans. 

entos-team-photo-credit-entos-pharmaceuticals-digest

Graphic showing Cas9 introducing blunt end double-strand breaks in DNA while Cas12a introduces staggered cuts in the DNA.

75365-ts-feb-02-25-digest-ac-cas9-and-cas12a-banner

What&rsquo;s the Difference Between Cas9 and Cas12a Nucleases?

3D illustration of a tumor on a black background. The tumor has recruited blood vessels to grow into it from a main artery running at the bottom of the photo. Around the tumor, purple, pink, and blue immune cells try to enter the tumor microenvironment but are stopped.

75365-ts-feb-02-25-digest-ac-interview-1800-x-1260

75365-ts-feb-02-25-digest-ac-interview-banner

Inducible CAR T Cells Target Solid Tumors Better

75365-ts-feb-02-25-digest-ac-crossword-1800-x-1260

75365-ts-feb-02-25-digest-ac-crossword-banner

Science Crossword Puzzle

Crossword Puzzle

A reimagined lipid vehicle for nucleic acids could overcome the limitations of current vectors. 