Image of forensic scientist Mitchell Holland. In the background there is someone in a white jumpsuit standing in front of caution tape.

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Image of a forensic scientist holding a magnifying glass to DNA to reveal a DNA fingerprint.

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Image of a forensic scientist holding a magnifying glass to DNA to reveal a DNA fingerprint. 

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DNA Profiling: Tracing Killers and Solving Mysteries Using Genetic Clues

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Photo of Holowatyj wearing a white lab coat. She is sitting at a laboratory bench and pipetting a liquid from a falcon tube.

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Illustration of a young adult looking at their phone as they walk through an arrow that is pointing up. An illustration of a colon is in the background.

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Generation X and Millennials Face a Steep Rise in Early-Onset Colorectal Cancer Cases

A red male cardinal and a brownish female sit on a branch in front of a green background.

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A black and white image of Nettie Stevens wearing a high-necked dress and a large hat.

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Richel Meisel wears a red collared shirt and stands in front of a light background.

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A tank filled with small fish in the laboratory.

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Judith Mank and a handful of other researchers observe tanks of guppies in the laboratory.

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A small brown mouse with a white underbelly.

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An underwater image of a snorkeler over a coral reef.

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Sex Determination: It&rsquo;s in the Genes&mdash;Sometimes

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Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against cancer.

Peto's Paradox: How Gigantic Species  Evolved to Beat Cancer

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

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Study Confirms Safety of Genetically Modified T Cells

TS Digest

Big Roles for the "Little Brain"

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old film photograph of skeletons found in Pompeii building

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Caught on Camera

Science Snapshot

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To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell&rsquo;s DNA damage response (DDR)&mdash;which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins&mdash;also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron&rsquo;s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

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DNA Damage Viewed with Unprecedented Clarity

Methods

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Illustration of the brain&#39;s cerebellum

A cross section illustration of a cerebellum

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The Cerebellum&rsquo;s Functions in Cognition, Emotion, and More

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Humsa Venkatesh Probes Cancer&rsquo;s Grip on the Brain

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Cartoon illustration of two scientists playing with miniature dinosaurs and meteors.

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Micrograph of a fragment of leaf cuticle showing epidermal cells (clustered) and a fern spore (bottom right) from a K-Pg site in southern Colorado

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Cartoon illustration of scientists playing with miniature dinosaurs and meteors.

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Ellen Currano and Alex Baer inspect plants in a greenhouse at the University of California, Santa Cruz.

Ferns bounced back much faster than other plants after the meteor impact that wiped out the dinosaurs.

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Why Did Ferns Persist When All Other Plants Perished?

Oysters’ shells were made into concrete and other materials used in construction during the Industrial Revolution.

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Oyster reefs form as the mollusks grow on a rocky underwater surface, each generation settling on the shells of the previous one.

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Divers assist on a project designed to draw oysters back to reefs in Australia.

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Oysters&rsquo; shells were made into concrete and other materials used in construction during the Industrial Revolution.

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Scientists Use Sound to Attract Baby Oysters Back to the Reef

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Cover of When Animals Dream: A colourful illustration of an octopus.<br><br>

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Cover of <em>When Animals Dream</em>: A colourful illustration of an octopus.

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Opinion: Animal Dreaming Should Give Us Ethical Pause

Article

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To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

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Infographic: DNA Damage Viewed with Unprecedented Clarity

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Illustration showing how a cerebellum can be divided into specific regions

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Infographic: The Cerebellum&rsquo;s Many Roles Beyond Motor Control 

The cerebellum is now appreciated for its functions in cognition, emotion, and other higher-order processes