An abstract illustration of a tooth on a bluish background, signifying teeth that are a source of multipotent dental stem cells that can have therapeutic applications in dental diseases and beyond.

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Stem cells in the teeth and gums are multipotent and easily accessible. Scientists are researching ways to harness their power for therapies beyond dentistry.

Dental Stem Cells Regenerate More Than Just Smiles

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus. 

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.

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What Is the Amniotic Fluid Composed of? 

TS Digest

The Scientist Top 10 Innovations 2022

PONG NEURONS: This is DishBrain, an in vitro system that combines human brain cells with artificial intelligence technology, which researchers at Australian biotech Cortical Labs recently trained to play the classic 1972 Atari video game Pong. Fluorescent markers show axons in green, neuron bodies in purple, dendrites in red, and all other cells in blue. Where multiple markers are present, colors are merged and typically appear as yellow or pink. Posted: October 12, 2022

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AIDING AND ABETTING: Scientists recently suggested that glioblastoma tumors (white) are supported by surrounding astrocytes (teal), which promote the growth and progression of cancerous cells by supplying them with cholesterol and remodeling immune cells. Posted: October 5, 2022

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CILIA BOOGIE: Researchers have discovered that primary cilia (green) on human beta cells in a pancreatic islet actively wiggle, perhaps to help the organ regulate insulin secretion. Posted: October 6, 2022

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This is DishBrain, an in vitro system that combines human brain cells with artificial intelligence technology, which researchers at Australian biotech Cortical Labs recently trained to play the classic 1972 Atari video game Pong. Fluorescent markers show axons in green, neuron bodies in purple, dendrites in red, and all other cells in blue. Where multiple markers are present, colors are merged and typically appear as yellow or pink. Posted: October 12, 2022

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SEEDING THE RAT BRAIN: An organoid grown from human cerebral neurons glows bright green inside a section of a rat brain. Scientists recently reported that the human cells matured successfully and integrated with rat neurons via synapses. Posted: October 12, 2022

SICKNESS ROOTS: Sickness behaviors, such as lethargy and loss of appetite, may emanate from specific neurons in the mouse brain (white). Researchers noted activation of these neurons (zoom on right) after they injected mice with a toxin that makes the animals act sick. Scale bars: 1 mm (left), 0.25 mm (right) Posted: September 23, 2022

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Caught on Camera

Science Snapshot

A wireless device implanted inside a rat brain shrinks cancer cells remaining after surgery. When triggered by ultrasound, the implant produces an electrical tumor-treating field (TTF) that interferes with proteins involved in cell division and triggers apoptosis in tumor cells. Healthy cells such as astrocytes, meanwhile, aren&rsquo;t disrupted by the electrical frequency emitted by the device, while neurons are unaffected because they don&rsquo;t divide. The researchers say that two implants would be used in humans, sandwiching the tumor.

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Implantable Device Zaps Cancer Cells Using Electric Fields

Methods

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Infographic: A Brain Implant Stops Tumor Growth in Rats

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Molecular
Cartography&trade;
Resolve Biosciences

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2022 Top 10 Innovations

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Can &ldquo;Gene Writing&rdquo; Deliver What Gene Editing Can&rsquo;t?

Article

An image of a pale, dead tree taken from the ground, so that the tree limbs stretch up into the sky.&nbsp;

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An image of a pale, dead tree taken from the ground, so that the tree limbs stretch up into the sky.

The Scientist Top 10 Innovations 2022

This year's top advances in sequencing, single-cell analysis, and more

Caught on Camera

Implantable Device Zaps Cancer Cells Using Electric Fields

Infographic: A Brain Implant Stops Tumor Growth in Rats

2022 Top 10 Innovations

Can “Gene Writing” Deliver What Gene Editing Can’t?

Certain Tree Species Are More Susceptible to Death by Lightning

Woolly Mammoth Genomes Reveal Genetic Adaptations to Cold

Opinion: Listening to the Biosphere Is Key Step in Saving It