Neuronal cell culture models allow scientists to investigate genetic and patient-derived disease contexts that are crucial for neurotoxicity studies. In vitro image-based neurotoxicity analyses often rely on immunohistochemistry-based techniques that are not only sensitive and specific, but also costly and time consuming. Live-cell dyes are convenient, inexpensive, and rapid neuron culture labeling alternatives. Additionally, automated microscopy and image analysis techniques support researchers performing high-content imaging across disciplines, generating large datasets for faster phenotypic screening.
Download this application note to learn about single-step labeling and high-throughput automated live-cell analysis for capturing complex and specific neuron responses.