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Modeling and Measuring Neurotoxicity in Live Cells

A robust, image-based neurotoxicity assay helps scientists streamline subcellular neuronal analysis with live-cell dyes and high-throughput automated microscopy.

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Neuronal cell culture models allow scientists to investigate genetic and patient-derived disease contexts that are crucial for neurotoxicity studies. In vitro image-based neurotoxicity analyses often rely on immunohistochemistry-based techniques that are not only sensitive and specific, but also costly and time consuming. Live-cell dyes are convenient, inexpensive, and rapid neuron culture labeling alternatives. Additionally, automated microscopy and image analysis techniques support researchers performing high-content imaging across disciplines, generating large datasets for faster phenotypic screening.

Download this application note to learn about single-step labeling and high-throughput automated live-cell analysis for capturing complex and specific neuron responses.

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