Hepatitis and liver disease

NEW YORK, 26 July (Praxis Press) The long-term viral and clinical patterns of hepatitis C virus (HCV) infection are unknown. Thomas and colleagues studied the incidence and determinants of viral clearance and clinical outcome in patients who acquired HCV by injecting drugs. Viral clearance occurred in about 10% of patients during a median follow-up of 8.8 years; clearance occurred more often in non-black patients and in non-HIV-infected patients. End-stage liver disease (ESLD) occurred in about


Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

NEW YORK, 26 July (Praxis Press) The long-term viral and clinical patterns of hepatitis C virus (HCV) infection are unknown. Thomas and colleagues studied the incidence and determinants of viral clearance and clinical outcome in patients who acquired HCV by injecting drugs. Viral clearance occurred in about 10% of patients during a median follow-up of 8.8 years; clearance occurred more often in non-black patients and in non-HIV-infected patients. End-stage liver disease (ESLD) occurred in about 2% of patients; ESLD was associated with greater age at baseline and higher weekly alcohol intake. Persistent viremia, in the absence of clinical liver disease, is the typical pattern of HCV infection; viral clearance and ESLD are rarer outcomes.

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
Share
3D illustration of a gold lipid nanoparticle with pink nucleic acid inside of it. Purple and teal spikes stick out from the lipid bilayer representing polyethylene glycol.
February 2025, Issue 1

A Nanoparticle Delivery System for Gene Therapy

A reimagined lipid vehicle for nucleic acids could overcome the limitations of current vectors.

View this Issue
Enhancing Therapeutic Antibody Discovery with Cross-Platform Workflows

Enhancing Therapeutic Antibody Discovery with Cross-Platform Workflows

sartorius logo
Considerations for Cell-Based Assays in Immuno-Oncology Research

Considerations for Cell-Based Assays in Immuno-Oncology Research

Lonza
An illustration of animal and tree silhouettes.

From Water Bears to Grizzly Bears: Unusual Animal Models

Taconic Biosciences
Sex Differences in Neurological Research

Sex Differences in Neurological Research

bit.bio logo

Products

Photo of a researcher overseeing large scale production processes in a laboratory.

Scaling Lentiviral Vector Manufacturing for Optimal Productivity

Thermo Fisher Logo
Collage-style urban graphic of wastewater surveillance and treatment

Putting Pathogens to the Test with Wastewater Surveillance

An illustration of an mRNA molecule in front of a multicolored background.

Generating High-Quality mRNA for In Vivo Delivery with lipid nanoparticles

Thermo Fisher Logo
Tecan Logo

Tecan introduces Veya: bringing digital, scalable automation to labs worldwide