You give me fever

By Elie Dolgin You give me fever James Gathany / CDC The paper: V. Nene et al., “Genome sequence of Aedes aegypti, a major arbovirus vector,” Science, 316:1718–23, 2007. (Cited in 100 papers) The finding: Five years after scientists sequenced the malaria vector Anopheles gambiae, researchers at the J. Craig Venter Institute and the University of Notre Dame released the genetic blueprint of

Written byElie Dolgin
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The paper:

V. Nene et al., “Genome sequence of Aedes aegypti, a major arbovirus vector,” Science, 316:1718–23, 2007. (Cited in 100 papers)

The finding:

Five years after scientists sequenced the malaria vector Anopheles gambiae, researchers at the J. Craig Venter Institute and the University of Notre Dame released the genetic blueprint of a second mosquito, Aedes aegypti, the species that spreads yellow and dengue fevers. With two mosquito genomes, researchers may develop genomics-based explanations of mosquito behavior and the pathogens they transmit, says Peter Atkinson of the University of California, Riverside.

The expansion:

Over the 150 million years since the mosquito lineages split, the Ae. aegypti genome ballooned to five times the size of A. gambiae’s. This enlargement was driven by a surge of transposable elements, which make up around half of Ae. aegypti’s 1.4 billion base pairs. “It’s still an open question as to why Aedes has so many” ...

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