Viral vectors introduce genes and gene editing sequences into cells, and are a popular platform for gene therapy due to their safety and efficacy features. Adeno-associated viral (AAV) vectors in particular have high transduction rates and reduced toxicity concerns compared to other viral vectors. However, these delivery vehicles present some application-specific challenges for scientists to consider and improve upon, particularly in the manufacturing space.
Download this compendium from The Scientist’s Creative Services Team and Polyplus, now part of Sartorius, to learn more about viral vectors for gene therapy and discover how to enhance recombinant AAV production.
Here is a look at what’s inside
- Article: Introduction to AAV Gene Therapies
- Poster: Viral Vector Platforms for Gene Therapy
- Case Study: Helper Plasmids Lend a Hand to AAV Production
