Gentra Systems' AUTOPURE LS Nucleic Acid Purification System
Automated nucleic acid purification systems capable of handling small samples (up to 1 ml) have become a time- and money-saving asset in recent years. However, clinical laboratories and clinical research groups requiring larger sample volumes have had to rely on time-consuming manual methods to purify nucleic acids--until now. Gentra Systems of Minneapolis has introduced the AUTOPURE LS system, the first instrument capable of isolating and purifying DNA and RNA from sample volumes of up to 10 ml.

The instrument uses Gentra's PUREGENE chemistry, which has been available as a manual DNA purification kit since 1992; it can also be adapted for use with the company's PURESCRIPT RNA isolation chemistry. Both methods are based on liquid-phase chemistries that eliminate the shearing that takes place with column-based preps, thus allowing users to isolate larger fragments 100-200 kb in length. The system...

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