Accelerating Antibody Discovery for Difficult Targets
Webinar

Accelerating Antibody Discovery for Difficult Targets

François Romagné will discuss how RNA immunization and single cell screening enhance antibody generation for poorly immunogenic proteins.

Share

This webinar will be hosted live and available on-demand

Monday, October 23, 2023 
11:00 AM Eastern Time (5:00 PM CET)

Scientists often use classical immunization strategies and hybridoma technologies to generate antibodies. However, when producing antibodies against poorly immunogenic targets, such as membrane proteins with short extracellular domains, these approaches achieve limited antibody diversity, making it difficult for scientists to select good candidates for pharmaceutical development. Innovative approaches that combine RNA immunization and single cell screening provide unique opportunities for researchers to dramatically speed up antibody discovery against such challenging targets. 

In this webinar brought to you by Bruker, François Romagné will present his work using mRNA immunization and single cell screening to obtain large collections of antibodies with molecular and functional diversity against a difficult-to-target G protein-coupled receptor and ion channel.

Topics to be covered 

  • Generating antibodies against difficult targets with mRNA immunization
  • Beacon® single cell screening technology for antibody discovery
François Romagné, PhD

 François Romagné, PhD
 Professor, ImmunoTechnology
 Aix Marseille University
 Scientific Director, MI-mAbs


Top Image Credit:

Accelerating Antibody Discovery for Difficult Targets

February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies