According to Protocol

Nearly all scientists involved in basic biomedical research are familiar with the "Red Book" (Current Protocols in Molecular Biology)1 and Molecular Cloning: A Laboratory Manual.2 These well-known, time-tested books are still considered "bibles" in research laboratories, containing a wide range of basic techniques used by most life scientists. However, as scientific studies and experimental designs become more intricate and specialized, so do the techniques involved. As a result, detailed, "spec

Written byBarbara Cunningham
| 8 min read

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Any basic research laboratory using molecular biology techniques will benefit from having a copy on hand of the newly published Third Edition of Molecular Cloning: A Laboratory Manual, by Joe Sambrook and David Russell, from Cold Spring Harbor Laboratory Press.2 Originally published almost 20 years ago, the first two editions of this book have been staples of molecular biology with a proven reputation for accuracy and thoroughness. According to Cold Spring Harbor Press representative Guy Keyes, this title continues to be the company's bestseller. Molecular Cloning is now sold as a three-volume set with an improved binding for enhanced durability.

Each chapter within the book describes how a particular technique was first developed, the theory behind how and why it works, and any modifications that have been made for enhanced success. There are a total of 18 chapters on topics such as plasmid usage in molecular cloning; working with bacteriophage ...

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