Interesting that you should suggest that we should not take the "Big Three" so seriously.1 Sir Hans Krebs was more than dismissive toward Nature. His advice to young scientists was not to publish in comics! He did, however, have a most interesting item [in Nature] (215:1244, 1967) on "The making of a scientist," clearly having put behind him the disappointment he must have experienced when a paper on his observations eventually leading to his Nobel Prize-winning discovery was rejected from their pages.
David Lloyd, Professor
Microbiology
PO Box 915
Cardiff University
Cardiff CF10 3TL
Wales,UK