Instrumentation for Microarray Production and Analysis - Part 1
Instrumentation for Microarray Production and Analysis - Part 2
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DNA microarrays are glass microslides or nylon membranes containing DNA samples (genomic DNA, cDNA, or oligonucleotides) in an ordered two-dimensional matrix. DNA microarrays can be used to analyze gene expression and genomic clones or to detect single nucleotide polymorphisms (SNPs).1,2 The DNA used to create a microarray is often from a group of related genes such as those expressed in a particular tissue, during a certain developmental stage, in certain pathways, or after treatment with drugs or other agents. Expression of that group of genes is quantified by measuring the hybridization of ...