Instrumentation for Microarray Production and Analysis - Part 1

Instrumentation for Microarray Production and Analysis - Part 2

Nanogen's NanoChip Cartridge
Today's molecular biology era can be defined by the dictum, "So many genes, so little time," and technologies for gathering genetic information are gaining speed. DNA microarrays are one of the most promising answers to that cry.

DNA microarrays are glass microslides or nylon membranes containing DNA samples (genomic DNA, cDNA, or oligonucleotides) in an ordered two-dimensional matrix. DNA microarrays can be used to analyze gene expression and genomic clones or to detect single nucleotide polymorphisms (SNPs).1,2 The DNA used to create a microarray is often from a group of related genes such as those expressed in a particular tissue, during a certain developmental stage, in certain pathways, or after treatment with drugs or other agents. Expression of that group of genes is quantified by measuring the...

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