Autism, in its early days

It's a small Keystone meeting on the pathophysiology of autistic syndromes here in Santa Fe, New Mexico, but you can feel the excitement among the 100 or so attendees, as they muddle their way through early data in this growing area of research. There are only nine posters being presented today -- but, according to co-host Pat Levitt from the Vanderbilt Kennedy Center, all are important. This is in contrast to the last Keystone I attended on stem cell biology in Whistler, British Columbia, in 20

Written byAlison McCook
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share
It's a small Keystone meeting on the pathophysiology of autistic syndromes here in Santa Fe, New Mexico, but you can feel the excitement among the 100 or so attendees, as they muddle their way through early data in this growing area of research. There are only nine posters being presented today -- but, according to co-host Pat Levitt from the Vanderbilt Kennedy Center, all are important. This is in contrast to the last Keystone I attended on stem cell biology in Whistler, British Columbia, in 2006, which was several times the size, with tens of posters every night. (Interesting, given that autism rates among children have skyrocketed, while the field of stem cell research has so far produced more hype than results.) So much about autism, a condition marked by socialization problems, remains a mystery - linkurl:genes;http://www.the-scientist.com/article/display/15820/ vs. environment, one disorder vs. multiple, the role of brain volume, etc. This morning, Gerry Dawson at the University of Washington described interesting experiments that attempt to linkurl:elucidate;http://www.the-scientist.com/news/display/52940/ some of the linkurl:clinical features;http://www.the-scientist.com/news/display/53818/ of autism. In one, scientists reviewed home video tapes taken of children at their first birthdays, and compared features of non-autistic children to those of children who were later diagnosed. In another photo, an autistic boy plays with blocks while a scientist sits across from him and pretends to be hurt and crying, to test how long it takes the boy to notice him, and how long he lingers over the sad scientist. As part of another experiment, the researchers broadcast two sounds: A woman inviting a child to play with her in a soothing voice, and a garbled computer sound with no recognizable words (the autistic children preferred the computer sound). One set of videos were encouraging: In one, a little girl sits and plays with blocks without looking at the people around her, and makes non-verbal sounds, all hallmarks of autism. After some intensive, early therapy, however, a second video shows the same girl reading, talking, smiling and engaging with those around her. A sign that some of what these scientists are doing may be working.
Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Meet the Author

Share
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Eppendorf Logo

Research on rewiring neural circuit in fruit flies wins 2025 Eppendorf & Science Prize

Evident Logo

EVIDENT's New FLUOVIEW FV5000 Redefines the Boundaries of Confocal and Multiphoton Imaging

Evident Logo

EVIDENT Launches Sixth Annual Image of the Year Contest

10x Genomics Logo

10x Genomics Launches the Next Generation of Chromium Flex to Empower Scientists to Massively Scale Single Cell Research