Baby bellies

By Victoria Stern Baby bellies © SPL / Photo Researchers, Inc. The paper: C. Palmer et al., “Development of the human infant intestinal microbiota,” PLoS Biol, 5:1556–63, 2007. (Cited in 101 papers) The finding: Chana Davis and her team at Stanford University School of Medicine designed a microarray to sequence small subunit ribosomal RNA (SSU rRNA) from microbes present in more t

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The paper:

C. Palmer et al., “Development of the human infant intestinal microbiota,” PLoS Biol, 5:1556–63, 2007. (Cited in 101 papers)

The finding:

Chana Davis and her team at Stanford University School of Medicine designed a microarray to sequence small subunit ribosomal RNA (SSU rRNA) from microbes present in more than 400 excrement samples from 14 healthy infants, starting with the first excrement after birth, to map out normal development of the gut ecosystem. They found that each individual infant had a unique microbial ecosystem that varied over time but remained distinct from other infants’. A pair of fraternal twins had gut environments that remained remarkably similar to each other over time, indicating the strong impact of environment.

The unexpected:

“We were surprised to find that each individual is really unique. There is no average baby,” says Davis (née Palmer).

The impact:

“This paper is one of the first and ...

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