Beating Malaria

Beating Malaria Mang We Tin with her feverish five-year-old son Hla Win Tun awaiting treatment at a clinic in Mawker Tie. Nicholas White and François Nosten have shown that artemisinin in combination with other drugs are 90% effective at fighting the scourge of the world. So why isn't everyone using it? By Merrill Goozner ARTICLE EXTRAS 1 Yet there is still little understanding of how artemisinin-based derivatives and the other drugs used i

Written byMerrill Goozner
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Nicholas White and François Nosten have shown that artemisinin in combination with other drugs are 90% effective at fighting the scourge of the world. So why isn't everyone using it?
By Merrill Goozner

If a research team led by Nosten and his mentor, Nicholas White of Mahidol University in Bangkok (whom many consider the world's leading malariologist), lead the way to better protocols for treating pregnant women and others with ACT, it won't be the first time that the duo has used the tools of clinical science to teach the world new methods for combating this age-old scourge. In 2001, the World Health Organization (WHO) declared ACT the preferred method for treating malaria, especially the most deadly form of the parasite, Plasmodium falciparum, which in most parts of the world has evolved resistance to older drugs such as chloroquine. WHO's 2001 decision was based largely on clinical trials that SMRU ...

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