Biochemist Glimcher Cited For Hard-Tissue Research

Surgeons know that some of the most painful, costly, deadly diseases could be prevented or reversed if only medical science understood the molecular structure of phosphated proteins and their interaction with calcium. No surprise then that Melvin Glimcher—who has been responsible for a number of extraordinary research breakthroughs in this area—would become the first person to receive the Bristol-Myers/Zimmer Award for Distinguished Achievement in Orthopaedic Research. Glimcher dir


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Glimcher director of the Laboratory for the Study of Skeletal Disorders and Rehabilitation at Children’s Hospital, Boston, and Harriet M. Peabody Professor of Orthopaedic Surgery at the Harvard Medical School, received the $25,000 award in recognition of his studies of how bones, teeth, arteries, and other tissues harden in the human body. He has identified five basic steps that lead to the hardening of tissue, as well as more than 10 unique combinations of phosphorus and proteins that attract calcium. Selected by an independent panel of leading orthopedic surgeons, Glimcher received the award during the American Orthopaedic Association annual meeting earlier this summer.

“The hardening of tissue is such a basic physical development in living creatures that the immense implications of Dr. Glimcher’s work are hard to grasp,” says Clement Sledge, a colleague of Glimcher’s at Harvard Medical School. “He is a pioneer in examining the molecular structure of phosphated ...

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