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J. Li, C. Yen, D. Liaw, K. Podsypanina, S. Bose, S.I. Wang, J. Puc, C. Miliaresis, L. Rodgers, R. McCombie, S.H. Bigner, B.C. Giovanella, M. Ittman, B. Tycko, H. Hibshoosh, M.W. Wigler, R. Parsons, "PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer," Science, 275:1943-7, 1997. (Cited in more than 270 papers since publication) Peter A. Steck Comments by Ramon Parsons , professor of pathology and medicine, Columbia University Cancer Center,

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J. Li, C. Yen, D. Liaw, K. Podsypanina, S. Bose, S.I. Wang, J. Puc, C. Miliaresis, L. Rodgers, R. McCombie, S.H. Bigner, B.C. Giovanella, M. Ittman, B. Tycko, H. Hibshoosh, M.W. Wigler, R. Parsons, "PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer," Science, 275:1943-7, 1997. (Cited in more than 270 papers since publication)

P.A. Steck, M.A. Pershouse, S.A. Jasser, W.K.A. Yung, H. Lin, A.H. Ligon, L.A. Langford, M.L. Baumgard, T. Hattier, T. Davis, C. Frye, R. Hu, B. Swedlund, D.H.F. Teng, S.V. Tavtigian, "Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers," Nature Genetics, 15:356-62, 1997. (Cited in more than 235 papers since publication)

Comments by Peter A. Steck, department of neuro-oncology, M.D. Anderson Cancer Center at the University of Texas Southwestern in Houston, and Sean V. Tavtigian, Director of Cancer Research, Myriad Genetics ...

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