Edited by: Paul Smaglik and Eugene Russo
R. Scully, J.J. Chen, A. Plug, Y.H. Xiao, D. Weaver, J. Feunteun, T. Ashley, D.M. Livingston, "Association of BRCA1 with Rad51 in mitotic and meiotic cells," Cell, 88:265-75, Jan. 24, 1997. (Cited in more than 235 papers since publication)

Comments by David M. Livingston, Emil Frei professor of genetics and medicine, Harvard Medical School, and chairman of the executive committee for research, Dana-Farber Cancer Institute

David M. Livingston
The tumor-suppressing ability of the infamous BRCA1 gene--which, along with BRCA2, has been linked to breast cancer1,2--was a complete mystery prior to the findings reported in this paper. Some had speculated that the gene's product served as a growth factor or a hormone. Senior author David M. Livingston and his colleagues at Harvard were the first to give some definitive indication as to where the gene might fit into the...

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