Scientists have charted the most complete cancer genomes to date, according to two studies published in Nature this week, providing a catalog of some 90% of all the somatic mutations in melanoma and a type of lung cancer, as well as a starting point for identifying potentially causal mutations common to these types of cancer.
Cross section of a human lung with cancer
Image: Wikimedia commons
"For the first time we have a really quite comprehensive view of two different common tumor types," said linkurl:Bert Vogelstein; of Johns Hopkins Medicine, who was not involved in the research. "That information will form the foundation for subsequent studies." Previously, scientists studying cancer genomes had identified a handful of so-called driver mutations -- those that have a causative effect on the cancerous growth. But these two papers are the first to also analyze the noncoding regions of the genome, which may also contain...

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