BD Biosciences-Discovery Labware's BD BioCoat™ Angiogenesis System for Endothelial Cell Invasion puts an end to the repetitious plate washing, manual cell scraping, and tedious cell counting associated with traditional in vitro cell culture insert methods. Designed to be automation friendly, the patented system allows for nondestructive, real-time evaluation and quantitation of endothelial cell invasion.

The BD BioCoat Angiogenesis System combines the properties of two of the Bedford, Mass.-based company's technologies: the BD Falcon™ HTS FluoroBlok™ and the BD Matrigel™ Matrix. The FluoroBlok inserts contain a proprietary polyethylene terephthalate membrane, with 3.0-µm pores, which is impregnated with dyes that absorb visible light from 490-700 nm with greater than 99 percent efficiency.

The Matrigel Matrix is a reconstituted basement membrane isolated from the EHS mouse sarcoma. Rich in extracellular matrix (ECM) proteins and enhancement factors, the matrix is composed of laminin, Collagen IV, enactin, and heparan sulfate proteoglycan. These ECM components...

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