Depression and mortality

NEW YORK, June 27 (Praxis Press) Studies on whether depressive symptoms are associated with mortality in the elderly have yielded contradictory findings. To address these discrepancies, Schulz and colleagues studied a population-based sample of 5201 men and women aged 65 years and older (see paper). They examined depressive symptoms and four categories of covariates at baseline, with the primary outcome measure being mortality after six years. Of the 5201 participants, 984 (18.9%) died within 6

| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

NEW YORK, June 27 (Praxis Press) Studies on whether depressive symptoms are associated with mortality in the elderly have yielded contradictory findings. To address these discrepancies, Schulz and colleagues studied a population-based sample of 5201 men and women aged 65 years and older (see paper). They examined depressive symptoms and four categories of covariates at baseline, with the primary outcome measure being mortality after six years. Of the 5201 participants, 984 (18.9%) died within 6 years. Participants with high baseline depressive symptoms showed a higher mortality rate (23.9%) compared to those with low baseline depression scores (17.7%). The researchers suggest that motivational depletion may be a key underlying mechanism for this effect. Depressive symptoms are an independent risk factor for mortality in community-residing older adults.

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies

Parse Logo

Parse Biosciences and Graph Therapeutics Partner to Build Large Functional Immune Perturbation Atlas

Sino Biological Logo

Sino Biological's Launch of SwiftFluo® TR-FRET Kits Pioneers a New Era in High-Throughout Kinase Inhibitor Screening

SPT Labtech Logo

SPT Labtech enables automated Twist Bioscience NGS library preparation workflows on SPT's firefly platform