Discouraging Hypotheses Slows Progress

If Einstein had been a biomedical scientist in the last part of the 20th century, he probably would have died without publishing anything and without making any contribution to science. Einstein was an entirely theoretical scientist: He never did an experiment and showed no interest in conducting experiments personally. The journal referees would have said that he had no experience in the field and that his ideas were mere speculations. Could biomedical science be losing Einsteins and near-Eins

Written byDavid Horrobin
| 6 min read

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All recent studies on the history and philosophy of science have emphasized that hypotheses and theories always come before observation and always condition what will be observed. The idea that scientists observe in a theoretical vacuum and only then incorporate their observations into a hypothesis or theory has been utterly discredited. All observations are theory-laden, and what is observed will always depend on the hypothesis held by the observer. Paradoxically, those most in thrall to theory are those who deny its importance: They fail to recognize that their own observations are dependent on the theories they hold.

Take one very simple example of which I have just become aware. In the late 18th and early 19th centuries one theory of brain organization held that the convolutions of the cerebral cortex were expressions of individuality and hence could exhibit no consistent pattern from person to person. Otherwise reliable observers carefully studied ...

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