'Drastic' Improvement Seen In Mass Spectrometers

Recent technological advances have vastly improved the mass range and resolution capabilities of mass spectrometers, while making these instruments more versatile and easier to use. “We can work with smaller and smaller amounts of material because the instrumentation sensitivities have improved so drastically over the last few years,” says J. Carter Cook, director of VG Instruments’ laboratory in Savannah, Georgia. Other improvements include advances in computerization t

| 4 min read

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

Recent technological advances have vastly improved the mass range and resolution capabilities of mass spectrometers, while making these instruments more versatile and easier to use.

“We can work with smaller and smaller amounts of material because the instrumentation sensitivities have improved so drastically over the last few years,” says J. Carter Cook, director of VG Instruments’ laboratory in Savannah, Georgia.

Other improvements include advances in computerization that permit more rapid processing of spectrometer information and improvements in ionization techniques, which give samples of the electric charge needed for detection and analysis. New ionization techniques have also allowed a greater variety of chemicals to be analyzed. The instruments use ions for their primary function: the identification and analysis of mass’ spectra, which are used to identify chemicals and deduce the structure of unknown compounds.

Part of mass spectrometry’s appeal is its versatility. The instruments can be modified to fit specific applications. ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Miles Weiss

    This person does not yet have a bio.

Published In

Share
Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Faster Fluid Measurements for Formulation Development

Meet Honeybun and Breeze Through Viscometry in Formulation Development

Unchained Labs
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo
An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

sartorius logo
Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

dna-script-primarylogo-digital

Products

Atelerix

Atelerix signs exclusive agreement with MineBio to establish distribution channel for non-cryogenic cell preservation solutions in China

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo
Singleron Avatar

Singleron Biotechnologies and Hamilton Bonaduz AG Announce the Launch of Tensor to Advance Single Cell Sequencing Automation

Zymo Research Logo

Zymo Research Launches Research Grant to Empower Mapping the RNome