Garage Innovation

The potential costs of regulating synthetic biology must be counted against putative benefits.

Written byRob Carlson
| 3 min read

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What to do about biohackers in the garage? The apparent answer from the US Presidential Commission for the Study of Bioethical Issues, whose first task has been to examine the emerging field of synthetic biology, is “prudent vigilance.”

It isn’t just tinkerers who are intrigued by the prospect of building genes and genomes. Many scientists are discovering exciting new ways to use synthetic DNA. Moreover, the exponentially decreasing cost of such DNA has encouraged innovative approaches to making drugs, biofuels, and other materials. As early as next year, synthetic biology may be used to produce flu-vaccine strains in days to weeks, rather than the 12 months now required.

Yet discussions of synthetic biology always include the din of warnings about artificial pathogens and Frankenstein experiments escaping the lab. Therein lies the rub for the commission: “Let science rip,” in the words of chair Amy Gutmann of the University of Pennsylvania, ...

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