Using a novel bioinformatics approach, researchers found that the majority of prostate cancers carry a specific gene fusion, a common feature of blood cancers but relatively rare in solid tumors, according to this week's
"There was a general consensus that the mechanism [of] translocation was not [found] in the major types of epithelial tumors," said Stephen Baylin at Johns Hopkins Medical School in Baltimore, Md., who did not participate in this study. "This is a big sort of hint that functional translocations are much more common in solid tumors. That's a fascinating step."
Chinnaiyan's lab at the University of Michigan Medical School had previously ...