An illustration of an mRNA molecule in front of a multicolored background.
Product

Generating High-Quality mRNA for In Vivo Delivery with Lipid Nanoparticles

Discover how mRNA modification, purity, and in vivo delivery affect expression and toxicity.

Share

mRNA-based vaccines and therapeutics are transforming the medical landscape by offering effective, targeted solutions for the prevention and treatment of various diseases. To generate these therapies, scientists require a simple and flexible workflow to synthesize high-quality capped mRNA and deliver it safely and efficiently in vivo.

Download this application note to learn about 

  • The advantages of an optimized mRNA synthesis kit
  • The differences between the Cap 1 and Cap 0 structures
  • The benefits of modifying mRNA and removing double-stranded RNA by-products
  • The in vivo performance of the synthesized mRNA when delivered using lipid nanoparticles

Sponsored by

  • Thermo Fisher Logo

Top Image Credit:

A greyscale image of cells dividing.
March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

View this Issue
Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Integra Logo
Explore polypharmacology’s beneficial role in target-based drug discovery

Embracing Polypharmacology for Multipurpose Drug Targeting

Fortis Life Sciences
3D rendered cross section of influenza viruses, showing surface proteins on the outside and single stranded RNA inside the virus

Genetic Insights Break Infectious Pathogen Barriers

Thermo Fisher Logo
A photo of sample storage boxes in an ultra-low temperature freezer.

Navigating Cold Storage Solutions

PHCbi logo 

Products

Zymo Logo

Zymo Research Launches the Quick-16S™ Full-Length Library Prep Kit

BIOVECTRA

BIOVECTRA is Honored with 2025 CDMO Leadership Award for Biologics

Sino Logo

Gilead’s Capsid Revolution Meets Our Capsid Solutions: Sino Biological – Engineering the Tools to Outsmart HIV

Stirling Ultracold

Meet the Upright ULT Built for Faster Recovery - Stirling VAULT100™

Stirling Ultracold logo