An illustration of an mRNA molecule in front of a multicolored background.
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Generating High-Quality mRNA for In Vivo Delivery with Lipid Nanoparticles

Discover how mRNA modification, purity, and in vivo delivery affect expression and toxicity.

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mRNA-based vaccines and therapeutics are transforming the medical landscape by offering effective, targeted solutions for the prevention and treatment of various diseases. To generate these therapies, scientists require a simple and flexible workflow to synthesize high-quality capped mRNA and deliver it safely and efficiently in vivo.

Download this application note to learn about 

  • The advantages of an optimized mRNA synthesis kit
  • The differences between the Cap 1 and Cap 0 structures
  • The benefits of modifying mRNA and removing double-stranded RNA by-products
  • The in vivo performance of the synthesized mRNA when delivered using lipid nanoparticles

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  • Thermo Fisher Logo

Top Image Credit:

©iStock, Christoph Burgstedt

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