Stem cell researcher linkurl:Shinya Yamanaka; will receive linkurl:this year's Kyoto Prize; in Advanced Technology for his work on generating pluripotent stem cells from adult tissues, the non-profit Inamori Foundation announced today (June 18).
Shinya Yamanaka
Image: The Lasker Foundation
In 2006, Yamanaka, currently a senior investigator at the Gladstone Institute of Cardiovascular Disease in San Francisco and a professor at Kyoto University, linkurl:presented his work; aimed at inducing pluripotency in somatic cells. Starting from a list of 100 proto-oncogenes and embryonic stem (ES) cell-associated transcripts, he and his colleagues at Kyoto University in Japan eventually whittled the list down to the four now-famed "Yamanaka factors," which, when introduced with retroviruses into mouse fibroblasts, appeared to revert the cells back to an embryonic-like state. The names of the four factors were not revealed, however, until the linkurl:research results were published; in Cell that August. Since then, Yamanaka's team has made numerous...
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