Magnetic separation of biomolecules and cells is finding increasing applications in both research and clinical laboratories because of its speed, simplicity, and low cost. Now the process has become even simpler and more efficient with the novel MixSep biomagnetic separation system offered by Sigris Research, Inc., of Brea, California. The MixSep combines mixing and separation in a single, compact instrument featuring a proprietary technology that generates a rotating magnetic field. Unlike most methods of magnetic separation, which involve moving liquid through beads by agitating the medium, this novel technology is based on a rotating magnetic field that induces levitation and dispersion of magnetic particles without agitation. Such mixing establishes a high rate of contact between particles and target substance, enhancing affinity-binding reactions. With a motionless medium, fluid turbulence and shear are eliminated, and integrating mixing and separation through a common mechanism simplifies automation.
This simple device:
- increases yield and purity...