Skip to main content

New Approaches to Discovery Push Research at Big Biotech

The biotechnology industry is among the biggest employers of life science professionals, with 140,000 employees generating $17.4 billion of revenue in 1997, according to an industry report by Ernst & Young LLP of Palo Alto, Calif. Since the birth of biotechnology in the 1970s, many of the seminal companies--such as Biogen and Genentech-- have matured into profitable or near- profitable companies. As these companies arose, venture capitalists fell in love with start-up biotechs in the 1980s

Written byJames Kling
| 6 min read

Register for free to listen to this article
Listen with Speechify
0:00
6:00

As the industry matures, larger companies change their research focus to reflect the success of the industry, while smaller start-ups seek niches that will allow them to survive into the future. What follows is a snapshot of cutting-edge research at five of the biggest, most successful biotech companies. The summaries, by no means a complete overview of the research at each company, represent a glimpse of the technologies and discovery programs that could drive big biotech research and development into the 21st century.


MULTIPLE FRONTS: Genentech has five main areas of research: cardiovascular, molecular oncology, endocrinology, neurobiology, and immunology.
South San Francisco, Calif. Genentech divides its efforts into five departments: cardiovascular research, molecular oncology, endocrinology, neurobiology, and immunology. In particular, the company puts a lot of research dollars into cancer and cardiovascular diseases, such as clotting disorders and heart disease.

In the past, Genentech has put about 75 percent of ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

Published In

Related articles background image
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

View this Issue
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad
Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

bioxcell
Scientist reviewing cellular and molecular data on a computer in a laboratory.

Building Translation-Ready Biomarkers with Connected Workflows

Danaher Logo

Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

Integra Logo
Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

Corning logo
Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
sino biological logo

Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays