New development in the field of Liquid Handling: Highly viscous substances such as collagen are now pipettable

Handling of volumes in the mL range of highly viscous liquids such as 99 % glycerol, detergents or collagen in the laboratory and for analytical purposes has proven difficult, requiring the use of suboptimal tools such as spoons. These requirements cause tremendous delays to analysis and mixing procedures.

Written byEppendorf
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

Handling of volumes in the mL range of highly viscous liquids such as 99 % glycerol, detergents or collagen in the laboratory and for analytical purposes has proven difficult, requiring the use of suboptimal tools such as spoons. These requirements cause tremendous delays to analysis and mixing procedures. As such, the precise volume of the liquid must frequently be determined via several material-intensive steps: in an initial time-consuming step, the highly viscous liquids are transferred between different vessels, followed by weighing and calculating the volume by consulting the liquid’s specific density.

In order to process aqueous liquids in precisely, modern laboratories also use pipettes with different functional principles, each equipped with the respective consumable tips. For viscous liquids in particular, those pipettes that function according to the direct displacement principle, similar to that of a syringe, have prevailed. However, increasing viscosity leads to growing flow resistance inside the tip. The ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies