New development in the field of Liquid Handling: Highly viscous substances such as collagen are now pipettable

Handling of volumes in the mL range of highly viscous liquids such as 99 % glycerol, detergents or collagen in the laboratory and for analytical purposes has proven difficult, requiring the use of suboptimal tools such as spoons. These requirements cause tremendous delays to analysis and mixing procedures.

| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

Handling of volumes in the mL range of highly viscous liquids such as 99 % glycerol, detergents or collagen in the laboratory and for analytical purposes has proven difficult, requiring the use of suboptimal tools such as spoons. These requirements cause tremendous delays to analysis and mixing procedures. As such, the precise volume of the liquid must frequently be determined via several material-intensive steps: in an initial time-consuming step, the highly viscous liquids are transferred between different vessels, followed by weighing and calculating the volume by consulting the liquid’s specific density.

In order to process aqueous liquids in precisely, modern laboratories also use pipettes with different functional principles, each equipped with the respective consumable tips. For viscous liquids in particular, those pipettes that function according to the direct displacement principle, similar to that of a syringe, have prevailed. However, increasing viscosity leads to growing flow resistance inside the tip. The ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
Share
A greyscale image of cells dividing.
March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

View this Issue
Stem Cell Strategies for Skin Repair

Stem Cell Strategies for Skin Repair

iStock: Ifongdesign

The Advent of Automated and AI-Driven Benchwork

sampled
Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Integra Logo
3D rendered cross section of influenza viruses, showing surface proteins on the outside and single stranded RNA inside the virus

Genetic Insights Break Infectious Pathogen Barriers

Thermo Fisher Logo

Products

dispensette-s-group

BRAND® Dispensette® S Bottle Top Dispensers for Precise and Safe Reagent Dispensing

Sapio Sciences

Sapio Sciences Makes AI-Native Drug Discovery Seamless with NVIDIA BioNeMo

DeNovix Logo

New DeNovix Helium Nano Volume Spectrophotometer

Olink Logo

Olink® Reveal: Accessible NGS-based proteomics for every lab

Olink logo