The P-glycoCHEK C219 priced at $550, is sufficient for 100 determinations. Potential applications include optimization of treatment protocols, prediction of therapeutic responsiveness, and identification of alternative treatment protocols. In addition, the C219 antibody is available for research applications involving immunobiochemical and immunocytochemical techniques.Centocor
New Monoclonal Antibody Detects Multidrug Resistance
A central area of investigation in cancer research and therapeutic treatment is the role of multidrug resistance (MDR) in neoplastic cells to a variety of chemotherapeutic compounds. Elevated levels of Pglycoprotein, an integral membrane protein that acts as a drug efflux pump, have been associated with the phenomena of MDR. High levels of P-glycoprotein expression have been identified in a variety of cell lines selected for resistance to various chemotherapeutic drugs. In addition, elevated lev
Written byWendy Wilson Sheridan
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