Concerning the relevance of animal experimentation to human health: Research in my laboratory is directed toward a better understanding of the mechanisms controlling reproductive function. We are very interested, in particular, in determining what can cause fertility disruptions.
In the course of one series of experiments carried out in rats, my colleagues and I noticed that repeated administration of analogs of the hypothalamic peptide that controls reproductive functions (gonadotropin-releasing hormone, GnRH) blocked gonadotropin and sex steroid release. We considered the possibility that injections with these peptides might represent a cure for some human diseases caused or exacerbated by high sex steroid concentrations.
After additional animal experimentation conducted byus as well as by other laboratories, and many years of clinical research and trials, there arenow several drugs on the market that do just that. These drugsare used for the treatment of disorders for which no prior adequate treatment was available, such ...
