NEW YORK, July 24 (Praxis Press) The differential diagnosis of arterial occlusive disease includes a host of conditions that cause embolism or thrombosis. Dingli and colleagues report a case of severe digital occlusive disease with an unusual infectious etiology. A woman with flulike illness subsequently developed cyanosis and pain in her fingers. Vascular studies revealed a fixed arterial occlusion, and an enzyme immunoassay revealed acute seroconversion for parvovirus B19. Parvovirus B19 infection can promote thrombosis of small arteries and should be included in the differential diagnosis of occlusive disease.

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