Skip to main content

Passive immunization and West Nile Virus

var FO = { movie:"https://images.the-scientist.com/supplementary/flash/53924/53924.swf", width:"520", height:"410", majorversion:"8", build:"0", xi:"true"}; UFO.create(FO, "ufoDemo"); Passive immunization and West Nile Virus By Edyta Zielinska In 1999, officials reported the first cases of West Nile Virus (WNV) in North America in eight New York City patients. Baxter Healthcare scientist Thomas Kreil realized that sera from infected patients might prote

Written byEdyta Zielinska
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00

By Edyta Zielinska

In 1999, officials reported the first cases of West Nile Virus (WNV) in North America in eight New York City patients. Baxter Healthcare scientist Thomas Kreil realized that sera from infected patients might protect others by passive immunization. The map above, adapted from the CDC, shows how quickly the virus spread west over the next four years. Human cases, usually asymptomatic, followed reports of animal infections. Serum pools collected from areas with high infection rates would have more anti-WNV antibodies. Read more about Kreil's experiments to test his hypothesis in this month's issue.

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

  • The Scientist Placeholder Image

    Edyta Zielinska was a senior editor at The Scientist from 2007 to 2013, where she worked closely with scientific illustrators to develop accompanying graphics to illuminate complex concepts. 

    View Full Profile

Published In

Related articles background image
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

View this Issue
Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

EpiCypher Logo
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Miltenyi
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad

Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

Integra Logo
Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

Corning logo
Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
sino biological logo

Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays