Photomicroscopy, circa 1876

Schematic drawing depicting Dr. J.J. Woodward's mechanism for taking photographs through a microscope. Inset: Histological preparations photographed by J.J. Woodward, circa 1876 Credit: Otis Historical Archives, National Museum of Health and Medicine, AFIP, Photo: © Jason Varney | Varneyphoto.com" />Schematic drawing depicting Dr. J.J. Woodward's mechanism for taking photographs through a microscope. Inset: Histological preparations photographed by J.J. Woodward, circa 1876 Credit: Otis His

Written byMichael Rhode
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

Photographs taken through microscopes are among the most basic tools of scientific research, but the techniques for doing so required the invention of appropriate cameras, and so are not even 150 years old. In the US, one of the people who developed the technique early on was J.J. Woodward, one of the Army Medical Museum's curators assigned to writing the medical part of The Medical and Surgical History of the War of the Rebellion.

Woodward took thousands of photographs in which he experimented with photomicrographs using sunlight, artificial lights and specialized stains. Woodward created masterful photomicrographs while using an entire darkened room as his camera. The schematic on this page shows that the lens was a microscope in a window, with a heliograph focusing sunlight though the slide and microscope. The image was projected onto a glass plate negative mounted in a wood box, two to four feet from the ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies