Cultured cells are used extensively in research, manufacturing, and for therapeutic purposes. Unfortunately, a large number of cell lines are mislabeled, contaminated, and misidentified, leading to results that are non-replicable, data that is erroneous, and conclusions that are faulty. These problems have often gone unnoticed and unchecked, costing labs a significant amount of time, money, and labor. The authentication of cell lines is a crucial quality-control step, and this webinar's experts will elaborate on some of the recent efforts underway to eradicate these problems.
Human Cell Line Cross-Contamination: 60 Years of Bad Practice, Ignorance, and Fraud
Dr. John Masters, Professor of Experimental Pathology, University College London; Director, Prostate Cancer Research Centre
Topics to be covered:
- Overview and history of cell authentication
- Current challenges and solutions
- Examples and case studies
Analytical Approaches to Authentication and Special Issues for Cells Intended for Clinical Use
Dr. Glyn Stacey, Head, Division of Cell Biology...
Topics to be covered:
- Analytical Techniques used for cell authentication
- Approaches for non-human cell lines
- Issues for identification of cell lines for clinical applications
Turning the Tide: Resources to Reduce Cross-Contamination and Avoid Misidentified Cell Lines
Dr. Amanda Capes-Davis, Founding Manager and Honorary Scientist, CellBank Australia; Chair, International Cell Line Authentication Committee (ICLAC)
Topics to be covered:
- The KB cell line story: why a new initiative is needed
- The database of cross-contaminated or misidentified cell lines
- The International Cell Line Authentication Committee (ICLAC)
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