Gene expression profiling of prostate cancer cells reveals a link between a polycomb group protein and metastasis or poor prognosis.
Prostate cancer becomes fatal when associated with metastasis. In the October 10
Varambally et al. identified 55 genes that were upregulated in metastatic versus localized tumors. They found that the gene encoding the polycomb group protein enhancer of zeste homolog 2 (EZH2) was significantly upregulated in metastatic cells and correlated with cancer progression. Disruption of
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A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.
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Explore how emerging biomarker research and ultrasensitive multiplex proteomics are revealing molecular signatures associated with neurodegeneration, inflammation, and disease progression in amyotrophic lateral sclerosis (ALS).
Explore practical strategies for designing, optimizing, and validating qPCR assays to improve specificity, reproducibility, and confidence across routine and high-throughput gene expression studies.
Explore strategies for navigating critical analytical decisions in single-cell RNA sequencing and spatial transcriptomics, from quality control and data integration to clustering, marker selection, and cell-type annotation.
Identify sources of variability and approaches for improving consistency across biomarker development.
Automation can help to increase efficiency and reproducibility, but often comes at a significant cost. The ASSIST PLUS pipetting robot streamlines workflows at an affordable price, offering accessible automation with minimal programming requirements.
Corning® Cell Strainers are sterile, easy-to-use devices for rapidly isolating primary cells to consistently obtain a uniform single-cell suspension from tissues. Applications include stem cells and primary cells.
Real time imaging shouldn't outlast your cell surface stain. CellBrite® Steady: cell surface staining kits with fluorescent membrane dye plus enhancer for imaging live cell surface for several hours to days.
Partnership brings Monod Bio’s LuxSit luciferase and NovoBodies to SignalChem Biotech’s custom assay services
