Prokaryotic Pioneer

By Karen Hopkin Prokaryotic Pioneer Always a trailblazer, Susan Gottesman laid the foundation for two new fields in bacterial gene regulation. © Jason Varney | varneyphoto.com As an undergraduate at Radcliffe College—Harvard's allgirl sister institution—in the 1960s, Susan Gottesman earned pocket money working as a technician in Jim Watson's Harvard lab. "I would hear stories of people going to mixers at

Written byKaren Hopkin
| 7 min read

Register for free to listen to this article
Listen with Speechify
0:00
7:00
Share

As an undergraduate at Radcliffe College—Harvard's allgirl sister institution—in the 1960s, Susan Gottesman earned pocket money working as a technician in Jim Watson's Harvard lab. "I would hear stories of people going to mixers at Radcliffe and meeting this strange guy who said he was a professor," she laughs. "But in the lab he was perfectly well behaved." And he encouraged Gottesman to get some hands-on experience by helping a grad student with his experiments. "I didn't know enough science to understand everything that was going on," she says. "But I got to do what I wanted, which was playing in a lab and learning through osmosis."

And through the years, Gottesman has certainly built on everything she's absorbed. As an independent investigator at the National Institutes of Health (NIH)—where she set up shop in 1976—Gottesman made major contributions in the field of prokaryotic gene regulation, uncovering key roles played ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

nuclera logo

Nuclera eProtein Discovery System installed at leading Universities in Taiwan

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo