Rat dad's diet affects pups

A father's high-fat diet may increase his offspring's risk of diabetes.

Written byMegan Scudellari
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

A father's diet can directly affect his daughter's health, according to a study in rats published today (October 20) in Nature.

For the first time, researchers have demonstrated a purported epigenetic link between a father's high-fat diet and an increased risk of disease in his offspring -- in this case, diabetes. Numerous papers have shown that aspects of a mother's health, including her weight, can have a significant impact on her offspring, but few have shown the same effect on the paternal side.

"It really does bring the father into play," said Michael Skinner, a researcher at the Center for Reproductive Biology at Washington State University, who was not involved in the study.

"This outcome suggests that our predisposition toward disease can be affected by what our parents or grandparents consumed during key points in their development," Tracy Bale of the University of Pennsylvania said in an email. Bale, who ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Meet the Author

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina

Products

nuclera logo

Nuclera eProtein Discovery System installed at leading Universities in Taiwan

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo