Skip to main content

Risk Assessment

The subject of cancer risk assessment (S. Brudnoy, The Scientist, March 8, 1993, page 14) is of continuing interest to academic scientists, but even more important to regulatory agencies. This topic is not as controversial scientifically as some may make it. All human carcinogens are genotoxic; that is, they can react under suitable conditions with DNA and genes, a fact leading to analytical detection. An exception as a nongenotoxic human carcinogen is high levels of the hormone diethylstilbest

Written byJohn Weisburger
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00

Another element that needs consideration, as described by Brudnoy, is the question of cell duplication rates. In any case, however, there are sound methods to evaluate human cancer risks. It is intriguing that there is so much intellectual discussion on cancer risks when the removal or modification of the documented known cancer risks--namely, tobacco use and nutritional excesses (especially in regard to fat intake)--that overall account for about 90 percent of the current cancer burden in the Western world, receives so little attention and readily implemented control measures.

JOHN H. WEISBURGER
Director Emeritus
American Health Foundation
Valhalla, N.Y.

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

Published In

Related articles background image
August 2026 Digest cover
August 2026

Epic Fail: Sea-Monkeys Sabotage Fieldwork

When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.

View this Issue
Improving rAAV Production for Viral Vector Manufacturing

Improving rAAV Production for Viral Vector Manufacturing

cytiva logo
Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Miltenyi
Overcoming Immunotherapy Resistance in Liver Cancer

Overcoming Immunotherapy Resistance in Liver Cancer

Axion Biosystems
Optimizing NGS Library Preparation for Reliable Sequencing Data

Optimizing NGS Library Preparation for Reliable Sequencing Data

Covaris

Products

Sino Biological Logo

Sino Biological Launches European Newsletter Campaign with Exclusive Welcome Gifts

Sino Biological Logo

Sino Biological Launches SuperNuclease ® Pro with Free Trial Program

Sino Biological Logo

Sino Biological Launches Precisely Characterized Full-Length p-Tau217 Protein to Advance Next-Generation Alzheimer’s Biomarker Assay Development

A photo of a scientist placing the Resipher device on a 96-well plate.

Resipher: Continuous Live-Cell Mitochondrial Respiration Monitoring in 96-Well Plates

Lucid Scientific logo