Rotavirus Vaccines, Take Two

Image: Courtesy of Umesh D. Parashar and Roger I. Glass HOMING IN ON THE TARGET: Rotavirus particles visualized by immune electron microscopy in stool filtrate from a child with acute gastroenteritis. The 70-nm particles possess a distinctive double-walled outer capsid. Ridding the world of smallpox was a triumph of 20th century medical science: Mass vaccinations directly averted some 350 million cases and saved 40 million lives. So, humanitarian hopes were similarly high when a rotaviru

Written byBob Beale
| 6 min read

Register for free to listen to this article
Listen with Speechify
0:00
6:00
Share

Ridding the world of smallpox was a triumph of 20th century medical science: Mass vaccinations directly averted some 350 million cases and saved 40 million lives. So, humanitarian hopes were similarly high when a rotavirus vaccine was developed in the 1990s with comparable potential to save young children from severe gastroenteritis.1-5 But that vaccine's controversial withdrawal from use ultimately put those hopes into limbo for years.

The optimism however, has reemerged with new vaccines that are in the pipeline. And perhaps within the next five years, the battle against rotavirus can be rejoined. Although public awareness is low, rotavirus is one of the world's worst infectious disease agents, killing up to 2,000 children a day.

Known as the democratic virus, rotavirus is highly contagious and can infect virtually everyone, regardless of their wealth, health, or hygiene standards. According to the National Institute of Allergy and Infectious Diseases (NIAID), the primary ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
July Digest 2025
July 2025, Issue 1

What Causes an Earworm?

Memory-enhancing neural networks may also drive involuntary musical loops in the brain.

View this Issue
Explore synthetic DNA’s many applications in cancer research

Weaving the Fabric of Cancer Research with Synthetic DNA

Twist Bio 
Illustrated plasmids in bright fluorescent colors

Enhancing Elution of Plasmid DNA

cytiva logo
An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

cytiva logo
Explore new strategies for improving plasmid DNA manufacturing workflows.

Overcoming Obstacles in Plasmid DNA Manufacturing

cytiva logo

Products

sartorius-logo

Introducing the iQue 5 HTS Platform: Empowering Scientists  with Unbeatable Speed and Flexibility for High Throughput Screening by Cytometry

parse_logo

Vanderbilt Selects Parse Biosciences GigaLab to Generate Atlas of Early Neutralizing Antibodies to Measles, Mumps, and Rubella

shiftbioscience

Shift Bioscience proposes improved ranking system for virtual cell models to accelerate gene target discovery

brandtechscientific-logo

BRANDTECH Scientific Launches New Website for VACUU·LAN® Lab Vacuum Systems